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KMID : 0370019910050000039
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Chung-Ang Journal of Pharmacal Sciences
1991 Volume.5 No. 0 p.39 ~ p.46
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Studies on the Heavy Metals Content in Scalp Hair of Children with Mental Retardation
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Abstract
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This study was carried out to study on the correlation between mental retardation and heavy metals in hair.
ICP Emission Spectrophotometer, model Perkin Elmer P40 was used for the analysis of heavy metals.
The mean value of lead, cadmium and calcium in hair of children with mental retardation were 15.36±2.57ppm, 1.16±0.14ppm, 1024.44±235.92ppm which are significantly higher than those of control group, 9.96±0.42ppm, 1.08±0.06ppm, 707.45±40.00ppm.
The contents of magnesium, manganese and iron in hair of children with mental retardation were 96.87±15.86ppm, 0.76±0.60ppm, 21.75±17.69ppm which are significantly lower than those of control group, 116.31±7.20ppm, 1.20±0.57ppm, 43.74±6.10ppm.
The contents of heavy metals in hair of children with mental retardation by sex was not significant. In the lead, there was significant negative correlation by IQ.
There was no significant correlation between heavy metals in scalp hair and mental retardation by types of handicap.
But, in mentally retarded children, the contents of cadmium and lead were higher level in hair of children with mongolism, speech disturbance, schizophrenia, autism and double handicap than that of children with no handicap.
In view of the whole results, the hypothesis that the lead will cause the mental retardation was partly reconfirmed.
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